Nature Biotechnology

Nature Biotechnology is interested in the best research from across the field of Biotechnology; our broad scope ensures that work published reaches the widest possible audience. All editorial decisions are made by a team of full-time professional editors.

Nature Biotechnology is a monthly journal covering the science and business of biotechnology. It publishes new concepts in technology/methodology of relevance to the biological, biomedical, agricultural and environmental sciences as well as covers the commercial, political, ethical, legal, and societal aspects of this research. The first function is fulfilled by the peer-reviewed research section, the second by the expository efforts in the front of the journal. We provide researchers with news about business; we provide the business community with news about research developments.

The core areas in which we are actively seeking research papers include: molecular engineering of nucleic acids and proteins; molecular therapy (therapeutics genes, antisense, siRNAs, aptamers, DNAzymes, ribozymes, peptides, proteins); large-scale biology (genomics, functional genomics, proteomics, structural genomics, metabolomics, etc.); computational biology (algorithms and modeling), regenerative medicine (stem cells, tissue engineering, biomaterials); imaging technology; analytical biotechnology (sensors/detectors for analytes/macromolecules), applied immunology (antibody engineering, xenotransplantation, T-cell therapies); food and agricultural biotechnology; and environmental biotechnology. A comprehensive list of areas of interest is shown below.

• Strategies for controlling gene expression
• Strategies for manipulating gene structure
• Strategies for gene containment
• Technologies for analyzing gene function (e.g., arrays, SAGE)
• Technologies for analyzing gene structure/organization (e.g., molecular beacons)
• Chemogenomics or chemical genetics
• Pharmacogenomics/SNPs
• Computational analysis
• Technologies for analyzing/identifying protein structure/function (e.g., 2-D gels, mass spectrometry, yeast two-hybrid, SPR, NMR, arrays and chips)
• Structural genomics
• Computational analysis
• Technologies for analyzing/profiling metabolites (chromatography, mass spectrometry)
• Computational analysis
• Bioinformatics; algorithms; data deconvolution
• Modeling and systems biology: kinetics-based models and constraints-based models
• Rational approaches for proteins/antibodies/enzymes/drugs
• Molecular evolution
• Molecular breeding approaches
• Genetic manipulation of species of interest to modify or allow the production of a commercially or therapeutically relevant compound
• Computational analysis
• Mammalian cells
• Insect cells
• Bacteria
• Fungi
• Plant cells
• Targeting strategies
• Viral and nonviral vector strategies
• Reporter molecules
• Imaging approaches/technologies for visualizing whole animals, cells, or single molecules
• Computational analysis
• Gene therapy (targeting, expression, integration, immunogenicity)
• Antisense
• RNAi
• DNAzymes and ribozymes
• Nanomaterials for use in drug delivery or as therapeutics
• Nanomaterials for use in industrial biotechnology
• Nanosensors
• Nanosystems for imaging molecules and cells
• Antibody engineering
• T-cell therapies
• Therapies exploiting innate immunity (e.g. complement)
• Antigen delivery vectors and approaches
• Nucleic acid vaccines
• Computational analysis
• Stem cells
• Tissue engineering
• Therapeutic cloning (somatic cell nuclear transfer)
• Xenotransplantation
• Biomaterials
• Approaches for detecting biological molecules
• Use of biological systems in detecting analytes
• Approaches for multiplexing and increasing throughput
• Selection/screening strategies for gene/proteins/drugs
• Microfluidics
• Engineering materials for biological application
• Molecular imprinting
• Biomimetics
• Nanotechnology
• Crop improvement (resistance to stress, disease, pests)
• Nutraceuticals
• Forest biotechnology
• Plant vaccines
• Plants as bioreactors
• Gene-containment strategies
• Transgenic animals
• Knockouts
• Reproductive cloning
• Biopharmaceutical and enzyme production
• Transgene targeting and expression strategies
• Bioremediation
• Biomining
• Phytoremediation
• Monitoring

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